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Wound healing activity of methanolic extract of leaves of Gossypium herbaceum | Abstract
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Central European Journal of Experimental Biology

Abstract

Wound healing activity of methanolic extract of leaves of Gossypium herbaceum

Author(s): C. Velmurugan*, S. Venkatesh, K. Sandhya, S. Bhagya Lakshmi, R. Ramsila Vardhan and B. Sravanthi

The present study was carried out to evaluate the effect of Gossypium herbaceum on experimentally induced wounds in rats and compare the effects observed with an antiseptic agent, povidine iodine ointment. The models selected were excision wound, incision wound and dead space wound. In incision and excision models, a significant decrease in period of epithelization and wound contraction was observed in all the treatment groups when compared to control. In the incision wound model, a significant increase in the breaking strength was observed. Granulation tissue formation significantly increased in all treated animals compare to control. It was concluded that extract administered orally (200mg/kg) possesses wound healing activity.