Der Pharmacia Lettre
Abstract
Author(s): D. Manjula and P. Venkata Ramana*
The electrochemical behaviour of 2-hydroxy-5-methyl benzophenone isonicotinoylhydrazone (HMBPINH) has been
studied in Britton-Robinson buffer solutions of pH 2.1 Ã?¢Ã?â?¬Ã?â?? 10.1. The compound exhibits two polarographic waves at
pH 2.1 and 4.1 while a single wave is observed at pH 6.1, 8.1 and 10.1. The waves are found to be diffusion
controlled and irreversible. In contrast to two waves observed in the polarographic studies three peaks are
observed in the cyclic voltammetric studies at pH 4.1. Similarly in contrast to a single wave observed at pH 8.1 two
peaks are observed in cyclic voltammetric studies. Coulometric studies indicated the involvement of eight electrons
in the reduction process. These waves are attributed to the four electron reductive cleavage of N-N bond and four
electron reduction of amide formed by the cleavage of N-N bond.
