A simple, accurate, specific and sensitive UV spectrophotometric method has been developed and validated for determination of Candesartan Cilexetil in bulk and tablet dosage form. The method is based on the measurement of absorbance of Candesartan Cilexetil in isopropyl alcohol at 306 nm. Beer’s law was obeyed over the concentration range of 10-90 μg/ml with correlation coefficient (r2 ) 0.999. As per ICH guidelines the method was validated for linearity, accuracy, precision, limits of detection (LOD), Limits of quantification (LOQ), and robustness and ruggedness. The proposed method was successfully applied for determination of Candesartan Cilexetil in tablets with good accuracy, precision and without any detectable interference from tablet excipients. The validity and reliability of the proposed method was assed by recovery studies.
