A prospective study to assess the outcome of the directly observed treatment short course (DOTS) in tuberculosis patients with HIV co-infection was conducted in Ojo Local Government in Lagos, Nigeria This study was carried out to determine the prevalence of HIV/TB co-infection among tuberculosis patients in DOTS centre in Lagos. This study was carried out between January 2013 and August, 2014 in Ojo Local Government (DOTS) centre, in Lagos, Nigeria. Five hundred and nine (509) DOTS attendees (270 females and 239 males, age-range 10-70years of age, at the Ojo and Okoko health services centre. Samples of sputum and blood were collected and processed using standard laboratory procedures. All the patients’ sera were screened for antibodiesforHIV1 2usingthree rapid ELISA kits. Sputum was examined for presence of mycobacterium tuberculosis using Ziehl-Nelseen staining method. A total of one hundred and twenty eight (25.1%) of HIV infection among diagnosed TB patients. HIV/TB coinfection positive patients for male and female were 25.6% and 24.8% respectively there is no significant difference (p>0.05). According to age, the prevalence in age group 15-24years and 25-34years were higher in female 20.0% and 30.4%while male were 14.2% and 27.6% respectively but in age 35-44years the prevalence was higher in male 21.8% while female was 15.2%. There was statically significant difference as regards the age related prevalence rate (P < O. 05). Early diagnosis and proper treatment monitoring condition must still be viewed with great concern with serious public enlightment campaign efforts to eradicate these twin devasting diseases.
