The purpose of this research was to determine the correlation between posture deformity and severity of depression in 15-18 years old kyphotic females. 150 kyphotic secondary students were recruited in city of Karaj in Iran during 2007 to 2008. The study was descriptive and the sample size was calculated by using random- cluster sampling method. The posture was assessed by using Plumb line and flexicurve ruler to address the presence of any thoracic kyphosis; the Aaron Beck standard questionnaire was administered to determine the severity of depression. Descriptive statistics were reported, and inferential statistics in the form of multiple regressions were conducted, Pearson’s correlation coefficient was used to analyze the findings; the results demonstrate that 81% of the participants who were diagnosed as to be clinically depressed according the Aaron Beck standard questionnaire were diagnosed as to be kyphotic