Like nanoorganisms (viruses), nanoparticles are able to enter cells and interact with cellular structures. Human exposure to toxic nanoparticles can be reduced through identifying creation-exposure pathways of toxins. In this work, we investigated the toxicity effect of cerium oxide nanoparticles on ALT, ALP and AST enzymes of male Rat. The cerium oxide nanoparticles synthesized and morphological properties of it such as UV-Vis spectrum characterization and transmission electron microscopy (TEM) were investigated. The enzymology studies were performed on 40 male rats that divided into five octet groups. The results showed that with increasing concentration of nanoparticles also increased levels of these three enzymes. And found linear equation between concentration of nanoparticles and levels of these three enzymes.
