In addition to bacteria, fungi, microeukaryotes, and viruses also coexist with bacteria in the mosaic ecosystems of microbes that inhabit human skin. Unique fungal communities, the second most common type, are present in the dry, moist, and oily microenvironments of human skin. Changes in these communities are mostly influenced by changes in skin physiology throughout an individual’s lifetime. Due to the disturbed equilibrium between fungal-bacterial networks on the skin, fungi have also been linked to infections and dermatological problems. The mechanisms of colonization resistance against fungus in animal skin microbiomes have enhanced our understanding of conservation methods, but the mycobiome (fungal microbiome) in human skin is still mostly unknown. Here, we review recent research on the function of fungi in the skin microbiome, highlighting the crucial ecological significance that fungalbacterial interactions at the skin surface play in vertebrate hosts.
