To determine the Sensitivity pattern of Escherichia coli to Amikacin in a tertiary care hospital. The study was done for a period of one year from March 2011 to February 2012. A total number of 464 patients were included in the study. The culture reports of these patients were analyzed which included urine samples from patients with urinary tract infections, pus of infected wounds, and blood culture of septicemia patients. The cultures which were positive for Escherichia coli were identified and their sensitivity towards Amikacin was tested. 44 strains of Escherichia coli were obtained comprising of 36 from urine samples, 5 from pus, 3 from blood culture. Of these 40 strains were found to be sensitive to Amikacin. Escherichia coli was found to be sensitive to Amikacin. Amikacin is found to be very effective in controlling infections caused by Escherichia coli.
