Calendula ,native to southwestern Asia, western Europe, Macaronesia, and the Mediterranean, is an annual and perennial herbaceous plants belongs to family Asteraceae . The aim of this study is to overview its pharmacological effects. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases up to 2016.totally, of 119 found articles, 40 articles were included. The search terms were “Calendula officinalis”, “therapeutic”, “pharmacological”, “herbal therapy”. Various studies have shown that Calendula officinalis possess anti-Pancreatitis properties, anti-Diabetic Properties, Anti-fungal Properties, Cytotoxic activity, anti-Tendon Properties, anti-Colitis Properties. Calendula is widely used for therapeutic and purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, essential oils, its stems and leaves demand further and more studies about the other useful and unknown properties of this multipurpose plant.
