To study the resistance pattern of Escherichia coli to Ciprofloxacin. Culture and sensitivity reports enrolling 464 number of patients over a period of one year was studied at Bhaskar Medical College. Cases which were culture positive for Escherichia coli were identified and their resistance pattern to ciprofloxacin was assessed. Out of 44 strains of Escherichia coli which were isolated 31 were resistant to ciprofloxacin and 13strains were sensitive to ciprofloxacin. Escherichia coli is more resistant to ciprofloxacin than other drugs like Levofloxacin, Nitrofurantoin, Amikacin, Gentamicin.
