A total of 100 patients suffering from CSOM were randomly selected from department of Otorhinolaryngology , Narayana Hospital, Narayana Medical College, Nellore. The ear discharge was collected and subjected to direct smear, aerobic culture and sensitivity. Direct smear examination and culture was positive in 93% of cases. Pseudomonas aeruginosa was the most predominant species in 40% of cases followed by Staphylococcus aurues in 31% of cases. Escherichia coli was present in 12% of cases and Proteus and Klebsiella in 5% each. Antibiotic sensitivity for Staphylococcus aureus was found to be sensitive to amoxiclav, Cefazolidone, erythromycin, azithromycin, clindamycin, netilmycin and gentamycin. They were resistant to amikacin, magnex and chloromycetin.
