For healthy and antibiotic free chicken meat products, use of antibiotics alternatives has been suggested. There was a little study about saccharomyces cervisiae beta-glucan effects on the broiler chicken, thus this experiment was undertaken to examine the effects of beta-glucan on serum total cholesterol, triglyceride and HDL. A total of 144 one day-old Ross-308 chicks (72 males and 72 females) divided into 18 groups (6 treatment and 3 replicate pens per treatment), and rations were balanced according to the Ross-308 guide catalogue. From first day, beta-glucan was added to diets. Data were analyzed based on a 2*3*3 factorial design with 2 sampling days (24 and 35 d), 2 bird sexes (male and female) and 3 concentration of beta-glucan (0, 0.04 and 0.08%). At the 24 and 35 days of the experiment, 6 birds per treatment (two from each pen) were randomly chosen and slaughtered. Birds fed betaglucan containing diets exhibited significantly effects on serum triglyceride and exhibited no effects on serum cholesterol and HDL. We found significantly effect on serum HDL in the male birds and in the female chicken, there was a significantly effect on serum total cholesterol and triglyceride. As well as we observed a significantly effect on serum HDL at the first sampling day (day 24) and at the second sampling day (day 35), there was a significantly effect on serum triglyceride and total cholesterol.
