The purpose of this study was to examine the effects of one year aerobic exercise training on basal leptin level in untrained healthy male and females. The subjects were divided randomly into female control (age: 25/26± 6/75 years, height: 164/125± 9/14 cm and BMI: 21/23 ± 0/50 kg/m2), female exercise (age: 24/98 ± 5/12 years, height: 166/375 ± 7/19 cm and BMI: 24/597± 1/27 kg/m2), male control (age: 24± 2/65 years, height: 174/375± 6/92 cm and BMI: 23/206± 0/53 kg/m2) and male exercise (age:23/125±1/93 years, height: 175/775 ±6/89 cm and BMI: 22/49±0/377 kg/m2) groups at first. The exercise protocol included a year of selected aerobic exercises and volleyball practices. Resting plasma leptin level was determined using ELISA method in pre and post tests and paired sample T test, one and two way (factorial) ANOVA were used to analyze the data . We failed to show any significant differences between pre and post test in any group or in the amount of changes observed in between pre andposttest between groups (P<0.05). Also, There were not significant effect of the sex, group (exercise/control) or their interaction upon the changes of leptin level between pre and post tests (P<0.05).With regard to the fact that not only the young subjects but also the controversial reports in the existing literature about obese and thin people were studied, it seems that other factors such as lifestyle or daily energy expenditure, etc, should be certainly investigated to drawn more obvious conclusions.
