The aim of this study was to determine effects of core stabilization training in postural control of subjects with chronic ankle instability. Thirty three male students were enrolled. Samples of this study composed of subjects with (n=22) and without (n=11) chronic ankle instability groups and also from samples with instability 11 persons select as a control group. Core stabilization training was performed for eight weeks by study groups. Star excursion balance test (SEBT) used for evaluation of subjects postural control. For statistical analysis the Repeated Measure ANOVA and POSTHOC bonfferoni tests were used (P≤0.05). The results revealed that core stabilization training make increase in postural control in healthy and chronic ankle instability subjects. Because the important role of core stabilizer muscles in control of extremities distal parts, it’s proposed that for rehabilitation of ankle sprain we should implement preventive exercise for body total kinetic chain.