Pain of muscles usually occurs after doing a new unusual physical activity, especially when associated with repeated eccentric contraction and then it gradually disappear. There is not an extensive agreement in the case of treatment methods of soreness sings quick reduction. This research with the aim of reviewing the effects of caffeine in 5 stages (24h before exercise, 12h before exercise, after exercise and 12h after it) and 1mg per 1kg of body weight on reduction of perceived pain on muscles, studied 16 female volleyball player with the mean age of 22 ± 2/5 years old in two caffeine and control groups. Amount of perceived pain was evaluated and compared in 2 groups. The result showed that caffeine is relatively effective in decreasing perceived pain muscles. It seems that coffee drinking causes decrease in pain. So suggested, athletes use this way for decreasing muscles perceived pain after the acute activity
