Diabetes mellitus is an important problem in human and also it occurs in many animals, particularly in pet. This study was to evaluate walnuts effects on serum concentration of glucose, triglyceride, Cholesterol, VLDL, LDL and HDL in experimental diabetes mellitus in rat. 30 male Wistar rats with age of 8 weeks and weight of 200 ± 20 grams were selected. Then these rats were divided into five groups, 6 rats per group. Diabetic treatment group and diabetic control group received subcutaneous a single dose of Alloxan (100mg/kg BW) in saline solution. Pour control group and control group received subcutaneous saline normal (100 mg/kgBW). After observed diabetes symptoms (Polydipsia, Polyuria,Glucosuria and Hyperglycemia) in groups that were received Alloxan, we have initiated to feeding treatment group and diabetic treatment group in the ratio of equal with walnuts and pellet. These groups were fed for 10 days. Blood samples collected from whole groups at the end of 10day. Evaluation of the serum levels of triglyceride revealed statistically significant differences in diabetic treatment group and treatment group with control group, but decreased significantly compared to the diabetic control group (P<0.05).Evaluation of the serum Levels of VLDL decreased significantly in diabetic treatment group and treatment group compared to the diabetic control group, but did not reveal statistically difference compared to the control group (P<0.05). Evaluation of the serum levels of HDL did not reveal statistically significant difference between groups (PËÃ?â??Ã?Æ?0.05). The walnut can be used as a natural fruit for prevent than diabetes mellitus disorders.
