The purpose of the present research was to determine the effect of sleep deprivation due to land travel on the concentration of Immunoglobulins A, G, and Mand serum cortisol in young soccer players. Thus, IgM, IgG, IgA, and serum cortisol concentration of 15 soccer players (mean and standard deviation of 18.40 ± 1.24 years of age, 167.66 ± 6.22 cm height, 66.6 ± 7.28 kg weight, and 23.60 ± 2.47 kg/m2 BMI) was measured after two trips from Gorgan to Tehran and Khorramabad. The subjects were selected using purposive and convenience sampling. Repeated measures analysis of variance was applied for data analysis. The results of Bonferroni correction revealed a significant increase in IgG, IgA, and serum cortisol concentration in Tehran ( ) and Khorramabad ( ), a significant increase in serum cortisol concentration between the two cities of Gorgan and Tehran ( ), a significant decrease in serum cortisol concentration between Tehran and Khorramabad ( ), and no significant difference in IgM concentration ( ). The results of the present research showed that sleep deprivationmay play an important role in immune and endocrine-related physiological function and suggest that quality and depth of sleep can be a more significant determinant for immune and endocrine function.
