Obesity increases the risk of various diseases. Leptin and insulin are hormones that are involved in regulating and balancing body weight and obesity. This research aims to explore the impact of intermittent exercise on serum concentration of leptin and insulin resistance in overweight female students. For this purpose, 30 female overweight volunteer students (BMI ≥ 26) of Azad University Parand Campus were selected and randomly divided into two groups: intermittent training group and control group. Training groups exercised for 12 weeks, three sessions a week with definite intensity and distance. Leptin, insulin, glucose, body weight, fat percentage, BMI And maximum oxygen consumption were measured both before and after the 12-week exercise. Using Independent T-test, the results showed that interval training had significant effect on leptin, insulin resistance index, body weight, fat percentage, BMI and maximum oxygen consumption (p ≤ 0.05). Therefore our findings support the hypothesis that intermittent exercise leads to significant decrease of leptin levels and insulin resistance.
