Annals of Biological Research
Abstract
Author(s): Reza Behmaram, Ali Asghar Aslaminejad, Mehdi Aminafshar and Mojtaba Tahmoorespur
With the availability of high-density marker maps and cost-effective genotyping, genomic selection(GS) methods
may provide faster genetic gain than can be achieved by current selection methods based on phenotypes and the
pedigree. Many schemes have been proposed for continuous traits, but methods for threshold traits are still scarce.
Accuracies for breeding values were investigated for a typical dairy cattle breeding setting by using genomic and
classic methods. Here we investigate some of the factors driving the accuracy of genomic selection, namely marker
numbers and heritability. In classic method, we estimated true breeding value(TBV) using ASReml from univariate
analysis model for threshold traits. Marker characteristics and linkage disequilibrium were obtained by simulation
to achieve a mutation drift balance. Six generations with only genotypes were generated to examine accuracy
changes rate over time. With h2= 0.05, accuracies for genomic and classic path ranged from 0.22 to 0.45 and 0.15
to .035 respectively. For genomic and classic methods with h2= 0.30, accuracies varied from 0.27 to 0.61 and 0.22
to 0.44 respectively. With h2= 0.80, accuracies for genomic and classic approaches ranged from 0.21 to 0.73 and
0.36 to .055 respectively. Results showed accuracies of breeding value by genomic selection were sufficiently high to
implement dairy selection schemes testing in which case a data time-lag of two to three generations may be present.
Using traditional method for estimating TBV resulted in reduced accuracies compared with direct genomic
selection.
