The present study attempts to investigate the effect of combined strength-endurance training program on the improvement of coronary disease risk factors in obese middle-aged men.Forty non-athlete healthy men with the age mean of 57/6±4/8 were selected from among the volunteers of this study. They were randomly divided to four groups of strength (n=10), endurance (n=10), combined strength-endurance (n=10) and control (n=10). To measure cardiovascular disease risk factors, blood samples were taken from the participants in two stages (before and after the training program) while they were fast. The training of the strength group included two sets of pyramidal strength training and the endurance group performed 30-min running with the intensity of 60-75% maximum heart rate. The training of the combined group included one set of pyramidal strength training and 15-min running with the intensity of 60-75% maximum heart rate for eight weeks (3 sessions per week). The research data were analyzed using a dependent t test for within-group evaluation and one-way Analysis of Variance (ANOVA) along with Toki post-hoc test for between-group evaluation(α<%5). The protocol included aerobic training with 60-75% maximum heart rate, three sessions per week for eight weeks. The control group continued their normal life during the period of study. The research findings showed that eight weeks of endurance, strength and combined training caused a significant increase in HDL-C concentration by 23%, 39% and 38%, respectively (P<%5). Also, eight weeks of endurance and combined training significantly decreased the LDL-C concentration by 18% and 18% and TC concentration by 6% and 7%, respectively (P<%5). Considering the research findings, combined strength-endurance training and endurance training are effective for improving heart coronary disease risk factors and middle-aged people can use these training programs in order to prevent from cardiovascular diseases
