The immune system is protecting the body against many invasive foreign materials. The aim of this study was to investigate the effect of an intense anaerobic exercise session on serum IgG, IgM and IgA levels in Handballist, Volleybalist and Climbist sports. In this study, 45 professional athletes with the mid age of 20-30 years old who have participated in the major leagues and the first batch of Zahedan city have been invited for this purpose. In this research, 30 second Wingate test was used to assess anaerobic power. Blood samples before, immediately after and 2h after exercises were collected and serum level of mmunoglobulins IgG, IgM ���� IgA concentration were measured by nephelometry. The results of this study indicated that the level of serum immunoglobulins IgG, IgM ���� IgA concentration in all three study groups before and after and two hours post exercise, did not significant change (P>0.05 ) .The results showed that short anaerobic exercise has not any effect on the level of immunoglobulins in athletes.
