Increment of lipoprotein(a) [LP(a)] Concentration, as a coronary artery disease risk factor. Probably LP(a) not been affected by physical activity and it is resistant against exercise stimulation. The aim of this cross-sectional study was to determine and compare of LP(a) concentration in selected groups. This analytical study was designed in three groups of subjects (15-25 yrs) who were voluntarily participated and randomly selected from Speed (age: 20.77 ± 3.14, BMI: 19.09 ± 0.97 kg/m²), semi-endurance (age: 19.70±3.42, BMI: 20.25±1.74 kg/m²) and endurance (age: 22.61 ± 2.96, BMI: 19.98 ± 2.32 kg/m²) runner females (N=3*13). Fasting serum concentration of LP(a) (Speed: 14.00 ± 9.55, semi-endurance: 17.00 ± 10.93 and endurance: 15.30±14.58 mg/dl) analysis with ELISA method. Data compared with Kolmogorov - Smirnov, Levine and ANOVA statistical tests (p≤0.05).Results demonstrated that differences of LP(a) concentration between groups were not significant (p= 0.813 , F(2,36)= 0.208). Comparison of LP(a) Concentration in speed, semi-endurance and endurance groups, to determine of different exercises training on this risk factor, were not significant. It seems that the findings of previous research and this study, LP(a) not been affected by exercise and it is resistance against training stimulation. Therefore physical activity has not any desirable effect on LP(a) concentration. So, to clarify the possible effect of exercise training on LP(a), more research `must be designed and implemented.
