The applications of the additive manufacturing technology for art and museum are numerous. The purpose of this study was to investigate the use of different 3D CAD/CAM systems, to identify opportunities and limitations in the field of museum conservation and restoration. 3D printing is a solution to recreate the objects and get detailed replicas. 3D printed replicas allow guests to give a new museum experience and to develop engagement and interactions with visitors. Other application of CAD/CAM technology includes helping people with visual impairment in the way of printing physical 3D representation of paintings. Additive manufacturing technology helps to recreate destroyed structures, damaged pieces, and missed details as a part of the restoration process. 3D simulation of the scanned objects allows manipulating fragile objects without damaging them, for example, to create diagrams for assembly of broken objects. The use of 3D reproductions is also a way to create virtual exhibits and to develop a new museum experience for the audience. Despite some limitations, CAD/CAM system is an important tool for museum conservations.