Der Pharmacia Lettre
Abstract
Author(s): Deepak Pareek, Manish Chaudhary, Pawan K Pareek, Ravi Kant, Kishan G Ojha, S M U Iraqi, Arun Pareek
Some N-(4/6-substituted-1,3-benzothiazol-2-yl)Ã?¢Ã?â?¬Ã?â??N'-phenyl thiourea derivatives (3) have been
synthesized by the reaction of substituted benzothiazoles with phenyl isothiocyanate in absolute
ethanol. These (3) were condensed with malonic acid in acetyl chloride to get 1-(4/6-substituted-
1,3-benzothiazol-2-yl)-3-phenyl-2-thiobarbituric acid derivatives (5). All the synthesized
compounds were characterized by elemental analysis, IR, 1H NMR and Mass spectral studies.
Compounds 3 and 5 were screened for their entomological and antibacterial activities.
