Gout is caused by high uric acid in the blood that leads to excess uric acid crystallizing in the joints causing swelling and pain. Uric acid is produced from the breakdown of the purine which is released when cells die or introduced from the food we eat. The enzyme that helps in breakdown of purine to uric acid is xanthine oxidase (XO). Allopurinol is a potent xanthine oxidase inhibitor. In present work synthesis of several novel Ce(III),Nd(III) compounds with allopurinol as heterocyclic ligand is reported.The ligand and metal complexes were characterized on the basis of elemental analysis, IR, UV spectral data, molar conductance, magnetic moment measurement, thermal analysis (TGA). Ce(III), Nd(III) complexes possesses octahedral geometry. The ligand and it’s metal complexes were screened for their antibacterial and antifungal activities.
