Complexes of Co(II), Ni(II), Cu(II), Zn(II), Mn(II) and Sn(II) with an antibacterial drug, 7-(a-amino-aphenylacetamido)- 3-methyl-3-cephem-4-carboxylic acid (cephalexine) as ligand were prepared and characterized by Infra red spectral analysis, elemental analysis and gravimetric analysis. The IR spectra revealed that the ligand is a bidentate and coordinated to the central metal ions through carboxyl group and β-lactam nitrogen. Elemental analysis showed that all the complexes have octahedral configurations, [ML2CL2], where L= Ligand and M= metal. Molar conductance measurement and decomposition temperature analysis indicated that all the complexes are stable non electrolytes chelates respectively. Antibacterial screening of the complexes against some bacterial isolate was also investigated. The complexes were found to have varied degree of inhibitory effect against the bacterial isolates (Staphylococcus aureus, Escherichia coli, Pseudomanous arigyana, klebsiella pneumonia and Salmonella typhy).
