A new series of 2-( 4-methyl -7-hydroxy-coumarin )-4-(cyclohexylamino)-6-(arylamino)-s-triazine have been synthesized. The novel compounds structure has been established on the basis of their substituted aryl amine derivatives. All the compounds were characterized by FT-IR, and 1H-NMR spectroscopy as well as elemental analysis. These new compounds were evaluated for their in vitro antibacterial activity.