Der Pharmacia Lettre
Abstract
Author(s): Vilas Shelar, Ravi Telkar, C.H.S. Venkataramana
Ethylchloroacetate and hydrazine hydrate were reacted with substituted aldehydes to get the
corresponding substituted N-benzylidine-2-chloro acetohydrazides, which were further
condensed with succinimide to get corresponding subsituted N-benzylidine-2-(2,5-dioxo
pyrrolidin-1-yl) acetohydrazides. These compounds were cyclized with thioglycollic acid to get
the corresponding thiazolidinone derivatives, which have been evaluated for their antimicrobial
activity.