The present investigation was carried out to compare feed based variations in Tilapia sp. and Anabas sp. The main objective of the experimental work was to assess: Variation in Length-Weight ratio, Changes in Protein content and associated indices like FCR, PER, PPV, Weight gain of Tilapia and Anabas sp. Okaya fish feed was taken for experimental work and the study was carried out from January- April, 2013 .