Due to large surface to volume ratio, the nano-scale structures have unique properties and dissolution behaviors which are expected to avoid the unwanted side effects and the higher conventional dosage levels in case of Active Pharmaceutical Ingredients (APIs). The suitable micro-emulsion is an interesting and potentially powerful alternative carrier for the targeted drug delivery. In the present study, well known API, 2-acetoxybenzoic acid or acetyl salicylic acid or Aspirin, nano-particles were obtained by W/O micro-emulsion technique, where AOT, nheptane and chloroform were taken as surfactant, oil phase and solvent, respectively. The micro-emulsion with synthesized Aspirin nano-particles was characterized by the Dynamic Light Scattering (DLS) for obtaining distribution of particle size, Transmission Electron Microscopy (TEM) for estimation of particle size and particle morphology and UV-Vis spectroscopy for the estimation of particle size and energy band gap. The particle size was found to be within 5 to 9 nm and the energy band gap was estimated to be 3.60 eV. The results are discussed.
