For study effects of nitrogen and potassium fertilizers on quantitative and qualitative characteristics of tobacco (male sterility variety PVH19) an experiment in factorial format based on randomized complete block design with 3 replications in Dyrakary Mahale Jvkandan Village (Talesh Township in Guilan Province located in north of Iran) in 2011 farming year was conducted. Factors of experiment were consisting of nitrogen fertilizer with three levels (N1: 0 (control), N2: 34.5 and N3: 69 kg pure nitrogen/ha from source of ammonium nitrate respectively 0, 100 and 200 kg/ha application) and potassium fertilizer with four levels (K1: 0 (control), K2: 75, K3: 150 and K4: 225 kg potassium oxide /ha from source of potassium sulfate respectively 0, 150, 300 and 450 kg/ha application). Measured traits were included leaf length, leaf width, number of leaves, stem diameter, plant height, leaf area index, fresh leaf yield, dry leaf yield, the average price, gross income, leaf chlorophyll content, nicotine content on priming, cutter and tip leaf, sugar content on priming, cutter and tip leaf, nitrogen content on priming, cutter and tip leaf, potassium content on priming, cutter and tip leaf. Results of data analysis showed that, the highest dry leaf yield between nitrogen fertilizer levels with 4501 kg/ha was recorded from 69 kg nitrogen/ha treatment. On the other hand, among potassium fertilizer application levels, the highest dry leaf yield with 4238 kg/ha was obtained from 225 kg potassium/ha usage. Between interaction treatments, the N3K4 level with 4975 kg/ha dry leaf yield was superior
