The present study was carried out to evaluate the anti-microbial properties of Antigonon leptopus against certain microbial strains causing dental carries (Micrococcus albus, Staphylococcus aureus, Proteus vulgaris and Pseudomonas aerogenosa.) using disc diffusion method. The flower extracts of Antigonon leptopus were prepared using solvents like ethanol and chloroform and are screened for its anti-microbial activity. The phytochemical screening of the flower extracts was performed. The anti-microbial activities of ethanol extract and chloroform extract of Antigonon leptopus flowers are checked by disc diffusion method. Both the flower extracts exhibited significant inhibition against these dental pathogens. Comparative study of the results obtained from the above methods indicates that the ethanol extract shows better antimicrobial activity against these strains. All the extracts showed concentration dependent activity comparable with the reference drug Streptomycin.
