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spectrophotometric determination and validation for Terbinafine hydrochloride in pure and in tablet dosage form | Abstract
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Abstract

spectrophotometric determination and validation for Terbinafine hydrochloride in pure and in tablet dosage form

Author(s): Krupa K. Patel, Bhavna H. Marya, and V. V. Kakhanis

Terbinafine Hydrochloride is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. The aim of this study was to develop simple, sensitive, cost effective,accurate, precise and rapid ultraviolet (UV) Spectrophotometric method for the estimation of Terbinafine Hydrochloride in pure form and its formulations. For the estimation of Terbinafine Hydrochloride, solvent system employed was methanol and wavelength of detection was 282 nm. The developed method was used to estimate the total drug content in commercially available tablet formulations of Terbinafine Hydrochloride.