Serum adenosine deaminase (ADA) activity serve as marker of diseases with altered cell mediated immunity. Gestational hypertension is multi factorial disorder of pregnancy affecting health of mother and fetus. In this study serum ADA levels were measured in gestational hypertensive women to understand role of cell mediated immunity in pathogenesis of gestational hypertension . Serum ADA levels in 50 gestational hypertensive women and 30 normotensive pregnant women were measured . Serum ADA level in gestational hypertensive women was higher than the normotensive pregnant women (64.84 ± 12.76 v 45.03 ± 8.80 , p < 0.001). This findings suggest that cell mediated immunity increases in gestationl hypertension.