Seroprevalence of Immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and Syphilis infections among pregnant women have been reported to be more common in Africa and Asia. This present retrospective study reports the seroprevalence of HIV, HBV, HCV and Syphilis among antenatal attendees in UMTH, Maiduguri-Nigeria. A total of 1105 pregnant women were tested for HIV, HBV, HCV and Syphilis. Eightythree of them (7.5%) were positive for HIV, this was followed by HBsAg with 76(6.9%) while the least was syphilis with 5(0.5%). The highest percentage prevalence for HIV infection was found in the age group 15-20years with 17(12.4%) while for HBV was found in age group 21-25years with 31(1.7%). HCV highest percentage positivity was found in 31-35years age group with 5(2.6%). The elderly pregnant women aged 46 – 50years were the lowest with no cases for any of the infections. Of the 1105 pregnant women tested, 11 (0.01%) had multiple infections. Of the 11 multiple infection, 9 (0.8%) were infected with HIV and HBV while 0.2% were infected with HIV and HCV. There was no co-infection of HBV and HCV, syphilis and HIV, HBV, HCV. Our study showed that it is very imperative for all pregnant women to be requested to test for HBV HCV alongside the conventional syphilis and HIV, infections to prevent them from infecting their unborn babies.
