The prevalence of new castle disease in chicken man in some state of Nigeria was investigated by a haemagglutinating antibody survey. A total of 879 sera (479 chicken and 400 humans) were tested .mean prevalence rate in man was 1.3% (12.6 in females and 14.8 in males) and varied from 8.3% to 60% in different age groups with median antibody titre of 1/64. Occupationally, prevalence rate ranged from 10.5% in civil servant to 28.8% in traders. Among apparently healthy chickens, prevalence rate ranged from 22.3% in Afikpo to 29.4% in Jos. The geometric mean antibody titre were 1.6 and 1.4 for Afikpo and Jos respectively. There is need to combat this disease through vaccination.
