Toxoplasmosis is a zoonotic disease caused by obligate, intracellular protozoan parasites, Toxoplasma gondii Nicole and Manceaux (Apicomplexa: Coccidia: Eucoccidiorida: Sarcocystidae) mainly causes abortion and still birth in humans and animals. The current research was conducted to determine the seroprevalence of toxoplasmosis and associated risk factors in goats, Capra hircus L in District Dir Upper (DU), Khyber Pakhtunkhwa (KP), Pakistan. Latex Agglutination Test (LAT) kit® was employed for this purpose. Agglutination at 1:16 dilution was considered positive. Antibodies were detected in 40 (n+) serum samples of the total 212 (ntotal) examined C. hircus showing an overall prevalence of 19%. The antibody titers to T. gondii positive sera were 7%, 5%, 5% and 2% by dilution of 1:16, 1:32, 1:64 and 1:128, respectively. Prevalence in males was 21% and in females 18%. There was no significant difference between toxoplasmosis and sex of C. hircus. Infection rate in young was 10% compared with 22% in adults. Difference between infection and age was statistically significant. Infection was higher in pregnant C. hircus than non-pregnant. There was statistically significant association between toxoplasmosis and history of abortion. Presence of cats, Felis catus L in vicinity of C. hircus and source of drinking water were found significant risk factors for toxoplasmosis. In conclusion, toxoplasmosis is common in C. hircus in DU and may be a risk for both animals and humans in this area. Therefore, appropriate measures should be taken to lower the risk of infection.
