Pyrazole derivatives possess various biological activities such as antimicrobial, anticonvulsant, antitubercular, antioxidant, antileishmanial, antiplatelet, antiviral, analgesic, anthelmintic, antimalarial, antitumor, anticancer and anti-inflammatory, etc. Pyrazole acts by inhibiting various enzymes which when produced or overexpressed can lead to various diseases or conditions. In the first part of the pyrazole review series, our focus is to report recent studies on bioactive pyrazole scaffold in enzyme inhibition mechanism.
