The study was undertaken to evaluate anti-aging effect of fenugreek seed extract(FSE) on the protein content,
amylase activity, fucose and sialic acid content of salivary glands of aging accelerated mice, because the protein
content and amylase activity decreases while the sialic acid and fucose content increases with age. So to evaluate
antioxidative property of fenugreek adult male albino mice (Mus musculus L.) were divided in to four groups viz, a)
Control group received subcutaneous injection of 0.5 ml sterile water for 20 days. b) D-galactose group received
subcutaneous injection of 0.5 ml 5% of D-galactose /day for 20 days. c) Protective group received subcutaneous
injection of D-galactose + FSE (50 mg/kg BW) for 20 days. d) Curative group received subcutaneous injection of Dgalactose
for 20 days then after FSE (50 mg/kg BW) for 20 days. In D-galactose injected group the protein content
and amylase activity was significantly decreased while sialic acid and fucose content were significantly increased as
compared to control group, but after treatment of FSE protein content and amylase activity was significantly
increased in protective and curative group, while sialic acid and fucose content were decreased. Thus above results
elucidate the antioxidative property of fenugreek seeds.
