Hyperlipidemia is a condition which characterized by presence of abnormal serum lipoprotein level in body fluids. Higher levels of serum lipid level can speed up the process called atherosclerosis and it leads to coronary heart disease (CHD). Based on survey done by National Commission on Macroeconomics and Health (NCMH), there will be more than 60 million case of CHD and majority will be identified with hyperlipidemia as the risk factor. The current study was a Prospective observational study which carried out in a 500 bedded tertiary care teaching hospital. And entire study population was analyzed to identify the risk factor with hyperlipidemia. Patients with age >60 years were identified with increased complications. Male were showing high prevalence rate than female with 52.1%. Other factors like Hypertension, diabetes, obesity, smoking, alcoholism, food habits and family history of hyperlipidemia were also identified. Mean SBP & DBP were found to be as 143.20±11.61mmHg and 89.86±36.18mmHg. In case of diabetes mean RBS was 208.54±86.92mg/dl, mean PPBS 213.64±72.35mg/dl and mean FBS levels 142.91±53.96mg/dl. Mean Body Mass Index (BMI) found to be 28.36±2.98kg/m2 and Waist circumference (WC) was 96.04±6.18cm. Serum Total Cholesterol and Triglyceride concentration shows high significance ratio when compared to Low density and High density lipoprotein in relation to the risk factors. It can be concluded that risk factors identified were both modifiable and non modifiable, hence through patient education and counseling the early detection and prevention could bring down morbidity and mortality rate of hyperlipidemia.