The phytochemical analysis of stem bark extracts in petroleum ether, chloroform, methanol and aqueous extracts of indigenous medicinally important plants of Tabernaemontana divaricata were investigated. The phytochemicals analysis reveals the presence of alkaloids, flavonoids, glycosides, lignins, saponins, tannins, carbohydrates, amino acids and quinines. This research supports the local use of the stem bark extract of the plant Tabernaemontana divaricata for treatment of fever. The present study provides evidence that solvent extract of Tabernaemontana divaricata contains medicinally important bioactive compounds and this justifies the use of plant species as traditional medicine for treatment of various diseases.