The present study deals with pharmacognostic, preliminary phytochemical and microbial screening of Achyranthes aspera. In this, pharmacognostical studies are concerned for the determination of physicochemical constants like ash values, extractive values, and loss on drying .The seeds were subjected to soxhlation using methanol petroleum ether ethyl acetate and water. The extracts thus obtained were studied for preliminary phytochemical screening for detection of presence of various classes of chemical principles viz., alkaloids, tannins, anthraquinone and phenol.