This study aimed to evaluate the hypoglycemic and hypolipidemic activity of aqueous seed extract of Chukrasia tabularis A.Juss a wild relative of Neem. The aqueous crude seed extract was aministred for 15 days in streptozotocin- induced diabetic rats. Administration of the extract at 400 mg/kg body weight significantly (Pvalues< 0.05) decreased blood glucose levels, and improved imbalance in lipid metabolism in diabetic rats. This significant result shows the best hypoglycemic action.