Many plants have been screened and found to be effective in the control of snails intermediate host of schistosomiasis, and for the control of mosquitoes responsible for malaria and many dangerous diseases of man, but such plants may not be available in all the areas where these diseases are endemic, hence the search for locally and readily available plants that can be use. This study was carried out based on the ethno-botanical uses of this plant which include treatment of infection and as a fish poison among many other uses. The study evaluated the larvicidal and molluscicidal potential of the leaves, stem and root barks of plant Albizia altissimum. Biomphalaria pffeiferii snails were used for molluscicidal test while 4th instars larvae of Aedes aegypti mosquitoes reared in the laboratory were used for the larvicidal test following the World Health Organization guidelines. The results showed that it was only the stem bark that exhibited different levels of activity against the organisms tested, with LC 50 of 125ppm and 50ppm for Biomphalaria pffeiferi snails and larvae of Aedes aegypti respectively. The LC 50 was determined graphically using a probit analysis table. The results confirmed the ethno-medicinal uses of the plant and it also confirm that plants used as fish poison also possess some level of molluscicidal properties and the potential of the stem bark for use as molluscicidal and larvicidal agents used in ethno-medicine.and an impetus for further research.