We present in this article syntheses of three new hybrids compounds (7, 10, 13) that were efficiently prepared in two or three steps from our previous prototype 5,6-diaminouracil with the NSAIAs (Diclofenac acid and Indomethacin) and 5-nitro-2-furaldehyde. The histamine chamber-aerosol induced method (5 ml of 1% w/v aerosoled in 1 min) is able to determine that all investigated new hybrids showed stronger bronchospasmolytic properties than their precursors.
