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Potency of mixed diet of garlic, garden egg and groundnut on some biochemical parameters of induced anaemic wistar rats | Abstract
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Annals of Biological Research

Abstract

Potency of mixed diet of garlic, garden egg and groundnut on some biochemical parameters of induced anaemic wistar rats

Author(s): M. A. Eluwa, T. E. Isamoh, A. O. Akpantah, O. R. Asuquo and T. B. Ekanem

This study aimed to evaluate the potency of consumption of mixed diet of garlic, garden egg and groundnut on some biochemical parameters. The animals were divided into five groups labelled 1, 2, 3, 4 and 5. Group 1 served as the non-anaemic control and were fed with normal rat chow. Groups 2, 3, 4 and 5 the experimental, were induced with anaemia by oral administration of phenylhydrazine (PHZ) given at 50mg/kgBW. Group 2 served as anaemic control, fed with normal rat chow; Group 3 were fed with 20g (75%ww) of garlic, garden egg and groundnut in the ratio of 1:1:1 with normal rat chow; Group 4 fed with 10g of garden egg (50%ww) in the ratio 1:1 with normal rat chow and Group 5 fed with 10g of groundnut (50%ww) in the ratio 1:1 with normal rat chow. Animals were sacrificed at the end of fourteen days of dietary feeding using chloroform inhalation method. Blood samples were collected by cardiac puncture for test of some biochemical parameters such as Total proteins, bilirubin and albumin. Total bilirubin was significantly (p<0.05) increased in Group 4 rats as compared to the positive and negative controls. Total protein level was significantly (p<0.05) reduced as compared to the positive control while Albumin level showed no significantly (p<0.05) among the five groups. Thus a mixed diet of garlic, garden egg and groundnut ameliorate the effect of anaemia on biochemical parameters.