Human beings like most organisms have defence and repair systems to fight against oxidative stress but at times these become inadequate to provide complete protection and here lies the need for antioxidant supplements. The present article focuses on the antioxidative activity of ethanolic extract of the mushroom Termitomyces microcarpus. A series of in-vitro assays were conducted with chelation of 50 % ferrous ion with only 0.14 mg/ml concentration, reducing power having 50% inhibition capacity at 1.65 mg/ml. Whereas DPPH and SOD assay gave EC50 values at 1.98 mg/ml and 0.295 mg/ml concentration respectively. Even presence of phytochemicals were recorded in the order of total phenol> total flavonoids> ascorbic acid> β carotene> lycopene. Hence, it can be suggested that ethanolic extract of Termitomyces microcarpus can be used as a good medicinal entity.
