The present research account is an investigation on the phytochemical content, antioxidant property and haemolytic activity of the whole plant crude extract of Curanga amara Juss.Plant extracts were prepared in three different solvents viz. petroleum ether, chloroform and methanol. Phytochemical screening showed the presence of different plant constituents. Alkaloids, phenolic, flavonoids, steroids and reducing sugar were detected in all three solvent extracts. Methanol extract was found to contain highest concentration (268.61±0.04, GAE/g) of phenol, while flavonoid content was highest (1118.67±0.08, QE/g) for the chloroform extract. Free radical scavenging assay against the 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) proved the strong antioxidant property of the plant. A highest of 98.74±0.01 free radical inhibition was achieved with methanol extract and the value was very close to that obtained with ascorbic acid standard (99.4±0.05). Haemolytic activity was tested for the methanol extract against goat blood normal erythrocytes. At 25mg/mL concentration, only 2.4% of haemolysis was observed for the extract, which suggested non-haemolytic nature of the plant compounds the extract contains. The findings of the present study provided a strong scientific background for recognizing this plant as potential medicinal herb used by many local tribes of North-East India.
