The aim of the present study was an attempt made in our laboratory to research for herbal-based anti-inflammatory products known to have beneficial effects of anti-inflammatory disorders in traditional medicines. The plant materials used for the anti-inflammatory activity were Curcuma longa, Bombax ceiba, Ficus bengalensis and Lens culinaris. Various in-vitro and in-vivo models have been proposed as being able to detect anti-inflammatory effect. A few of these methods have been symmetrically evaluated for their potential usefulness in screening beneficial effects on acne. The result obtains by MECL, MEBC was 50.06% suppression where as other combination MECL and MEFB are 45.97% and MEFB and MEBC was 35.50% and a combination of MECL, MEFB and MEBC was 31.35 % suppression in paw oedema volume which is extremely significant as comparable to standard drug indomethacin 10mg/kg.
