The majority of European nations' adoption of selective bio-waste collection offers new potential for the anaerobic digestion industry. Parallel to this, during the past 10 years, significant progress has been made in the creation of biodegradable plastics such polylactic acid and poly hydroxy-butyrate, which make it easier to replace traditional plastics. This study looked into anaerobic co-digestion of bio-waste and biodegradable polymers in semi-continuous reactors. According to estimates, phb completely biodegraded in the reactors. In contrast, pla accumulated in the reactor, and at the third hydraulic retention time, an average biodegradation was predicted. The biodegradation yield of pla was boosted by thermo-alkaline hydrolysis pretreatment. Finally, it was made clear that adding pla or phb to the feed had no further impact on the digestate’s agronomic characteristics